Spindle US | Science-Led Metabolic Health Brand

Powered by Akkermansia MYO™
Clinically proven results.

The first daily postbiotic designed
for the gut-muscle connection

Muscle strength that starts in your gut.

Your gut is a communication hub that sends signals throughout your body, including to your muscles. This is known as the gut-muscle connection. is the first targeted daily postbiotic designed to optimize this communication to help build muscle strength.

Clinically proven to support muscle health

Clinically proven muscle strength gain²

Works alongside GLP-1 to help preserve lean muscle mass¹

Restores gut barrier integrity³

Optimizes the gut-muscle connection³

Kang et al., Nutrients, 2024. Based on a randomized, placebo-controlled 12-week study of Akkermansia MYO™ in adults ages 60+ (mostly women). Mechanism of action and basic science support broader expected benefits. Individual results may vary based on biology, lifestyle, and other individual factors.
Third-party clinical study, data on file. Based on a randomized, placebo-controlled 12-week study of Akkermansia MYO™ in adults ages 60-80 (mostly women). Mechanism of action and basic science support broader expected benefits. Individual results may vary based on biology, lifestyle, and other individual factors.
Depommier et al., Nature Medicine, 2019. Based on a 3-month clinical study of pasteurized Akkermansia in overweight or obese adults with insulin resistance and metabolic syndrome. Individual results may vary.

The strength and precision of

Through a complex process of heat-treated pasteurization, Akkermansia MYO™ is optimized to deliver consistent performance from capsule to body to preserves muscle and increases strength

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The hidden burden of muscle loss.

Starting around your mid-30s, you begin losing approx 0.5% of muscle tissue per year. By your 80s, you may lose around 20% of the muscle mass you had at your peak. Strength falls far faster than muscle mass — it can decline 2–5× faster than mass. This gap can be a strong predictor of falls & loss of independence.

Spindle muscle+ supplement packaging on a bathroom counter with Muscle+ Akkermansia product.

Two women lying on grass with a Spindle Muscle+ bottle, clinically proven to support muscle health.

Close-up of a person's eye with a finger pointing to the iris, showing a measurement of 1.6cm, suitable for GLP-1 users.

Two white capsules with colorful geometric shapes and text about high potency and protein coding sequences on a dark blue background.

Hand holding a small white pill with text 'Pasteurized for consistency & stability' on a light gray background

Spindle supplement container with colorful gel-like objects on a white background

Spindle supplement label with detailed ingredient list and directions on a blue background

Gut strong.

Body stronger.

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Woman wearing a blue shirt against a dark background

Guided by science.

Meet our expert advisor, Dr. Marcia C. Haigis, Professor of Cell Biology and Co-Director of the Paul F. Glenn Center for Biology of Aging Research at Harvard Medical School.

ABOUT SPINDLE